Proton Transfer Can Govern Regioselectivity Assisted by Iron Catalysis
نویسندگان
چکیده
منابع مشابه
Proton Transfer in Ribozyme Catalysis
This chapter provides an overview of recent progress in understanding proton transfer in RNA enzymes. It was over 10 years ago that the previous book by the same editors was published. In that volume, there was no chapter on proton transfer. Indeed, it was unclear whether proton transfer made important contributions to RNA catalysis. Many things have changed in the last decade. Most importantly...
متن کاملSolvent-mediated proton transfer in catalysis by carbonic anhydrase.
Considerable attention has been focused on proton transfer through intervening water molecules in complex macromolecules of biological interest, such as bacteriorhodopsin, cytochrome c oxidase, and many others. Proton transfer in catalysis by carbonic anhydrase provides a useful model for the study of the properties of such proton translocations. High-resolution X-ray crystallography in combina...
متن کاملWater-assisted proton transfer in ferredoxin I.
The role of water molecules in assisting proton transfer (PT) is investigated for the proton-pumping protein ferredoxin I (FdI) from Azotobacter vinelandii. It was shown previously that individual water molecules can stabilize between Asp(15) and the buried [3Fe-4S](0) cluster and thus can potentially act as a proton relay in transferring H(+) from the protein to the μ(2) sulfur atom. Here, we ...
متن کاملSynthesis of 1-(isopentyloxy)-4-nitrobenzene under ultrasound assisted liquid-liquid phase-transfer catalysis
In this paper, we report the reaction of isoamyl alcohol and 1-chloro-4-nitrobenzene was carried out in a batch reactor under aqueous-organic biphasic conditions using the techniques like phase transfer catalysis and ultrasound irradiation. Tetrabutylammonium bromide (TBAB) was employed as the phase transfer catalyst. The reaction is greatly enhanced by adding a small quantity of phase-transfer...
متن کاملEnzymatic Catalysis of Proton Transfer and Decarboxylation Reactions.
Deprotonation of carbon and decarboxylation at enzyme active sites proceed through the same carbanion intermediates as for the uncatalyzed reactions in water. The mechanism for the enzymatic reactions can be studied at the same level of detail as for nonenzymatic reactions, using the mechanistic tools developed by physical organic chemists. Triosephosphate isomerase (TIM) catalyzed interconvers...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: iScience
سال: 2020
ISSN: 2589-0042
DOI: 10.1016/j.isci.2020.101214